Moxifloxacin, an antibiotic, can sometimes trigger allergies in people. Symptoms of a moxifloxacin allergy may include rash, itchiness, difficulty breathing, and swelling of the face, lips, or tongue. To diagnose this allergy, doctors usually rely on the patient's medical history and specific tests. Treatment typically involves immediately discontinuing the medication and managing symptoms, which can range from antihistamines for mild reactions to epinephrine for severe ones. Always seek immediate medical help if you suspect a moxifloxacin allergy.