Tag: PPI and fluconazole
Proton Pump Inhibitors and Antifungals: How They Interfere with Absorption and Effectiveness
Proton pump inhibitors can reduce the absorption of certain antifungals like itraconazole and ketoconazole, leading to treatment failure. Fluconazole is safer to use with PPIs, but newer research suggests PPIs might actually boost antifungal effects in some cases.